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. 2015 Aug 25;11:1486–1493. doi: 10.3762/bjoc.11.161

Table 3.

Extending the scope of the tandem CEYM–IMDAR protocol to amides 8.

graphic file with name Beilstein_J_Org_Chem-11-1486-i017.jpg
entry 8 9 10 % yield 10a
(endo: exo)b
1 8a –c graphic file with name Beilstein_J_Org_Chem-11-1486-i018.jpg 85
(93:7)
2 8b graphic file with name Beilstein_J_Org_Chem-11-1486-i019.jpg graphic file with name Beilstein_J_Org_Chem-11-1486-i020.jpg 78
(53:47)
3 8c –c graphic file with name Beilstein_J_Org_Chem-11-1486-i021.jpg 47
(66:34)
4 8d –c graphic file with name Beilstein_J_Org_Chem-11-1486-i022.jpg 68
(72:28)
5 8e –c graphic file with name Beilstein_J_Org_Chem-11-1486-i023.jpg 25
(77:23)
6 8g –c graphic file with name Beilstein_J_Org_Chem-11-1486-i024.jpg 33
(50:50)

aIsolated yields after column chromatography; bdiasteroisomeric ratio determined by 1H NMR; cnot observed;