Table 3.
Clinical characteristics of participants with glycated hemoglobin of 6.0–6.4%
| Bodyweight loss (%) |
Bodyweight gain (%) | ||||
|---|---|---|---|---|---|
| ≥4.3% | ≥2.5 to <4.3% | ≥1.2 to <2.5% | 0 to <1.2% | ||
| n | 17 | 22 | 20 | 21 | 67 |
| Age (years) | 55.3 ± 4.6 | 52.5 ± 7.4 | 53.2 ± 5.7 | 54.1 ± 7.7 | 53.2 ± 7.0 |
| Body mass index (kg/m2) | 25.9 ± 1.8 | 26.4 ± 3.7 | 26.1 ± 2.8 | 27.2 ± 2.7 | 26.1 ± 2.4 |
| Obesity† (yes/no) | 12/5 | 14/8 | 11/9 | 16/5 | 42/25 |
| WC (cm) | 91.7 ± 4.5 | 92.1 ± 7.3 | 90.7 ± 5.5 | 94.6 ± 7.4* | 91.0 ± 5.4 |
| eVFA (cm2) | 138.7 ± 22.9 | 135.7 ± 33.8 | 130.6 ± 24.5 | 147.3 ± 34.1* | 133.0 ± 24.2 |
| Fasting plasma glucose (mg/dL) | 110 ± 9 (4) | 104 (2) | 109 ± 6 (3) | 113 ± 6 (5) | 107 ± 8 (9) |
| Causal plasma glucose (mg/dL) | 118 ± 23 (13) | 114 ± 20 (20) | 127 ± 31* (17) | 108 ± 21 (16) | 111 ± 25 (58) |
| HbA1c (%) | 5.7 ± 0.1* | 5.8 ± 0.1 | 5.8 ± 0.2 | 5.8 ± 0.2 | 5.8 ± 0.1 |
| Systolic blood pressure (mmHg) | 139 ± 19 | 140 ± 21 | 140 ± 19 | 141 ± 16 | 133 ± 24 |
| Diastolic blood pressure (mmHg) | 87 ± 13 | 85 ± 13 | 86 ± 13 | 87 ± 11 | 85 ± 9 |
| Total cholesterol (mg/dL) | 215 ± 27 | 225 ± 44 | 207 ± 38 | 212 ± 32 | 218 ± 36 |
| Triglyceride (mg/dL) | 209 ± 109 | 279 ± 260* | 211 ± 99 | 205 ± 151 | 194 ± 119 |
| LDL cholesterol (mg/dL) | 123 ± 26 | 122 ± 38 | 114 ± 29 | 119 ± 30 | 126 ± 32 |
| HDL cholesterol (mg/dL) | 52 ± 14 | 54 ± 16 | 52 ± 15 | 54 ± 19 | 54 ± 10 |
| Family history of diabetes (yes/no) | 1/16 | 3/19 | 4/16 | 3/18 | 18/49 |
| WC change (%) | −7.1 ± 3.3 | −3.3 ± 3.5 | −1.6 ± 3.3 | −0.8 ± 3.0 | 1.9 ± 3.5 |
| eVFA change (%) | −26.6 ± 12.4 | −8.6 ± 12.8 | −8.8 ± 10.9 | −2.4 ± 12.6 | 5.1 ± 11.6 |
| Bodyweight change (%) | −7.5 ± 2.4 | −3.4 ± 0.6 | −1.8 ± 0.4 | −0.7 ± 0.3 | 2.8 ± 2.6 |
Data are mean ± standard deviation, numbers in parentheses represent available data.
*
P < 0.05, compared with the weight gain group.
†
Obesity was defined as body mass index of ≥25 kg/m2.
eVFA, estimated visceral fat area; HbA1c, glycated hemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein; WC, waist circumference.