Figure 2.

Reduced CD3+ B220+ CD4− CD69+ T cell subpopulation in kidneys and lungs from carbon monoxide (CO)-treated lupus mice. Murphy Roths large (MRL)-Faslpr and MRL-MpJ mice were treated with CO 250 parts per million (ppm) 5 days/week from weeks 9 to 15. Graphs represent the percentage and absolute counts of: CD3+ B220+ CD4– T cells from kidney (a,b) and lung (c,d); CD3+B220+CD4−CD69+ T cells from kidney (e,f) and lung (g,h). Absolute counts are presented as cells ×106 per mg of tissue of three independent experiments; nmice/group = 5, three independent experiments. *P < 0·05, **P < 0·01, ***P < 0·001 by one-way analysis of variance (anova) test. Data shown are the mean ± standard error of the mean.