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Patterns of BCR/ABL gene rearrangements involving the m-bcr breakpoint (p190 BCR/ABL) as revealed by FISH analysis of interphase-cultured BM nuclei cells showing two different patterns: nuclei with two fusions (typical m-BCR/ABL gene rearrangements) and nuclei with three fusions, including an extra signal corresponding to supernumerary Ph chromosome, in addition to the two fusion signals typical of m-BCR gene rearrangements.
