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. 2015 Sep 22;17(1):130. doi: 10.1186/s13058-015-0640-x

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© Mehmeti et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Toll-like receptor 4 (TLR4) expression in breast tumors and survival curves. a Immunohistochemical TLR4 expression sample images from breast cancer tissue microarray cores, from left to right: negative (0), weak (1), moderate (2), strong (3) and very strong (4). Boxes with magnification and arrows to indicate localization (black arrow membranous, green arrow leukocyte, red arrow cytoplasmic staining. b Kaplan-Meier curves illustrating differences in recurrence-free survival according to TLR4 cytoplasmic expression in breast tumors. Cytosolic scoring parameters were grouped into 0–2 (0) and 3–4 (1) critical cutoffs. c Gene expression profile analysis of TLR4 mRNA in relation to IL-6 in (R2: microarray analysis and visualization platform [40]; Tumor breast EXPO-351)