Table 1.

Clinical characteristics of EoE cases and non-EoE controls

	Non-EoE controls (n = 87)	EoE cases (n = 61)	p
Age at diagnosis (mean ± SD)	51.9 ± 13.2	38.8 ± 13.2	< 0.001
Male (n, %)	37 (42)	36 (58)	0.05
White (n, %)	73 (82)	58 (94)	0.04
Symptoms/EGD indication (n, %)
Dysphagia	71 (80)	60 (97)	0.002
Heartburn	60 (67)	10 (16)	< 0.001
Abdominal pain	5 (6)	7 (11)	0.21
Nausea/vomiting	8 (9)	1 (2)	0.06
Atopic disorders (n, %)
Asthma	19 (21)	19 (31)	0.20
Atopic dermatitis	7 (8)	4 (6)	0.74
Allergic rhinitis/sinusitis	40 (45)	40 (65)	0.02
Food allergies	10 (11)	28 (45)	< 0.001
Any atopic disease	48 (54)	46 (74)	0.01
EGD findings at baseline (n, %)
Normal	13 (15)	3 (5)	0.06
Rings	8 (9)	47 (76)	< 0.001
Stricture	19 (21)	15 (24)	< 0.001
Narrowing	2 (2)	16 (26)	< 0.001
Furrows	3 (3)	55 (89)	< 0.001
Crêpe-paper	3 (3)	4 (6)	0.38
White plaques/exudates	3 (3)	27 (44)	< 0.001
Decreased vascularity	3 (3)	37 (60)	< 0.001
Erosive esophagitis	17 (19)	2 (3)	0.004
Schatzki’s ring	13 (15)	7 (11)	0.55
Hiatal hernia	51 (57)	8 (13)	< 0.001
Baseline max eosinophil count (mean ± SD)	2.8 ± 6.8	146.3 ± 128.4	< 0.001
Median eosinophil count (IQR)	0 (0-2)	111 (60-165)	< 0.001
Follow-up max eosinophil count (mean ± SD)*	-	54.5 ± 87.9	-
Median eosinophil count (IQR)	-	9 (0-84)	-
Histologic response rates
< 1 eos/hpf	-	17 (28)	-
< 15 eos/hpf	-	33 (55)	-

^*n = 60 EoE cases with follow-up biopsy data