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. Author manuscript; available in PMC: 2015 Sep 22.
Published in final edited form as: Methods Mol Biol. 2015;1268:43–66. doi: 10.1007/978-1-4939-2285-7_3

Table 8.

Classification of 3D structures of antimicrobial peptides

Structurea K/R ratio Peptide count Examples
α 13.65/5.26=2.59 329 Cecropin, dermcidin, LL-37, magainin
β 5.63/10.7=0.53 97 Human alpha defensins (HNP-1, HNP-
4, and HD-5), plant kalata B1
α β 8.47/7.05=1.2 81 Drosomycin, Human beta defensins
(HBD-1, HBD-4), PhD1
Non-αβ 4.85/10.19=0.48 9 Indolicidin, tritrpticin, drosocin, nisin
A
a

For AMPs without 3D structures, additional annotations were made in the APD: (1) unknown, no 3D structure; (2) bridge, disulfide-linked, usually beta-structure; (3) rich, rich in certain amino acids.