Table 5. Summary of DENV Virus Kinetics in Rhesus Macaques.
Table reports median days to viremia and duration of viremia with 95% bootstrap confidence intervals for 5th, 25th, 50th, 75th, and 95th percentile.
| Serotype | Percentile | Time to Viremia Days (95% CI) |
Duration Days (95% CI) |
|---|---|---|---|
| 1 | 5th | 1.43 (1.20, 1.68) | 2.02 (1.73, 2.44) |
| n = 97 | 25th | 2.35 (2.08, 2.64) | 3.31 (2.97, 3.76) |
| 50th | 3.32 (3.01, 3.65) | 4.67 (4.27, 5.12) | |
| 75th | 4.69 (4.28, 5.11) | 6.59 (6.01, 7.18) | |
| 95th | 7.73 (6.89, 8.57) | 10.82 (9.51, 12.12) | |
|
| |||
| 2 | 5th | 0.98 (0.82, 1.18) | 2.24 (1.98, 2.59) |
| n = 155 | 25th | 1.76 (1.55, 2.00) | 3.65 (3.35, 4.00) |
| 50th | 2.63 (2.40, 2.89) | 5.13 (4.82, 5.48) | |
| 75th | 3.95 (3.67, 4.22) | 7.21 (6.73, 7.70) | |
| 95th | 7.06 (6.48, 7.64) | 11.76 (10.48, 13.01) | |
|
| |||
| 3 | 5th | 1.30 (1.07, 1.57) | 1.03 (0.84, 1.33) |
| n = 75 | 25th | 2.14 (1.85, 2.41) | 2.02 (1.73, 2.41) |
| 50th | 3.02 (2.71, 3.34) | 3.22 (2.83, 3.72) | |
| 75th | 4.26 (3.78, 4.74) | 5.14 (4.56, 5.84) | |
| 95th | 6.99 (5.91, 8.13) | 10.05 (8.70, 11.58) | |
|
| |||
| 4 | 5th | 1.44 (1.32, 1.58) | 1.10 (0.95, 1.31) |
| n = 139 | 25th | 2.32 (2.16, 2.51) | 2.04 (1.83, 2.32) |
| 50th | 3.23 (2.99, 3.47) | 3.13 (2.86, 3.46) | |
| 75th | 4.49 (4.12, 4.84) | 4.82 (4.38, 5.28) | |
| 95th | 7.22 (6.48, 7.89) | 8.96 (7.96, 10.00) | |