Table 4.
Baseline characteristics of studied patients with T2DM.
| Variable | DSPN No | DSPN Yes | p value |
|---|---|---|---|
| Patients number | 42 | 42 | |
| Male/female, No. (%) | 23 (54.8)/19 (45.2) | 27 (64.3)/15 (35.7) | 0.34 |
| Age (years) | 60.1 ± 7.5 | 66.2 ± 9.3 | 0.0001 |
| Height m2 | 1.65 ± 0.06 | 1.68 ± 0.07 | 0.04 |
| Weight kg | 85.4 ± 13.8 | 83.0 ± 12.7 | 0.40 |
| Age at diabetes diagnosis (years) | 53.7 ± 8.5 | 55.5 ± 10.8 | 0.38 |
| Diabetes duration (years)∗ | 5.5 (1–17) | 10 (1–29) | 0.0006 |
| GSTP1, No. (%) | |||
| Ile/Ile | 26 (61.9) | 23 (54.8) | 0.68 |
| Ile/Val | 12 (28.6) | 12 (28.6) | |
| Val/Val | 4 (9.5) | 7 (16.7) | |
| GSTT1, No. (%) | |||
| Null | 8 (19.0) | 7 (16.7) | 0.76 |
| Present | 34 (81.0) | 35 (83.3) | |
| GSTM1, No. (%) | |||
| Null | 22 (52.4) | 18 (42.9) | 0.38 |
| Present | 20 (47.6) | 24 (57.1) | |
| Body mass index (kg/m2) | 29.2 ± 4.3 | 31.1 ± 5.1 | 0.05 |
| Systolic BP (mmHg) | 152.5 ± 22.2 | 154.2 ± 28.4 | 0.75 |
| Diastolic BP (mmHg) | 89.1 ± 9.8 | 90.5 ± 17.1 | 0.62 |
| Hypertension (yes), No. (%) | 40 (95.2) | 41 (97.6) | 0.55 |
| Creatinine (mg/dL) | 0.87 ± 0.18 | 0.94 ± 0.28 | 0.04 |
| Blood urea nitrogen (mg/dL) | 36.8 ± 12.6 | 42.3 ± 15.7 | 0.08 |
| HDL cholesterol (mg/dL) | 43.5 ± 11.8 | 41.8 ± 12.2 | 0.52 |
| LDL cholesterol (mg/dL) | 110.3 ± 33.5 | 108.5 ± 52.2 | 0.84 |
| Total cholesterol (mg/dL) | 184.7 ± 40.7 | 184.3 ± 63.3 | 0.97 |
| Triglycerides (mg %)∗ | 142.4 (70–286.1) | 153.1 (59.1–798.0) | 0.92 |
| Microalbuminuria (mg/L)∗ | 3.9 (3–234.1) | 13.5 (3–1293) | 0.006 |
| HbA1c | 6.95 ± 1.01 | 7.3 ± 1.2 | 0.24 |
| Statins (yes), No. (%) | 24 (57.1) | 30 (71.4) | 0.17 |
| Fibrates (yes), No. (%) | 1 (2.4) | 1 (2.4) | 0.98 |
| Insulin (yes), No. (%) | 13 (31.0) | 23 (54.8) | 0.02 |
Data are shown as mean ± SD, as median (min-max), or as OR: odd ratio, CI: confidence interval, and No.: number.
∗Mann Whitney test, DSPN No: without DSPN, and DSPN Yes: with DSPN.