Table 1.
Knockout mouse models of globozoospermia.
| Mouse model | Protein name | Round head | Acrosome | Coiled tail around the nucleus | Reference |
|---|---|---|---|---|---|
| Gopc | Golgi-associated PDZ and coiled-coil motif-containing protein | Yes | Absent | Yes | [3] |
|
| |||||
| Agfg1 (Hrb) | ArfGAP with FG repeats 1 | Yes | Absent | Yes | [15] |
|
| |||||
| Zpbp | Zona pellucida binding protein | Yes | Absent | Yes | [17] |
|
| |||||
| Spaca-1 | Sperm acrosome associated 1 | Yes | Absent | Yes | [18] |
|
| |||||
| Dpy19l2 | Dpy-19-like 2 (C. elegans) | Yes | Absent | ? | [19] |
|
| |||||
| AKR-bs X 129 | ? | No (elongated) | Absent | No | [23] |
|
| |||||
| Gba2 | Beta glucosidase 2 | Yes | Present (deformed) | No | [24] |
|
| |||||
| Pick-1 | Protein interacting with C kinase 1 | Yes | Present (deformed) | No | [25] |
|
| |||||
| Csnk2a2 | Casein kinase 2, alpha prime polypeptide | No (oval) | Present (deformed) | Yes | [26] |