Table 2.
Association of depressive/anxiety symptoms with death, dialysis, and hospitalization in CKD patients
| Events | Incidence a | |||||
|---|---|---|---|---|---|---|
| BDI < 11 | BDI ≥ 11 | BDI < 11 | BDI ≥ 11 | BDI ≥ 11 | BDI ≥ 11 | |
| (n) | (n) | Unadjusted model | Adjusted model b | |||
| Dialysis/Death | 24 | 19 | 13.2 | 25.8 | 1.9 (1.0 – 3.5)* | 2.1 (1.0 – 4.2)* |
| Composite event c | 44 | 30 | 35.7 | 81.7 | 2.0 (1.3 – 3.3) | 2.0 (1.2 – 3.5) |
| Death | 10 | 9 | 5.5 | 12.2 | 2.2 (0.9 – 5.4) | 1.5 (0.5 – 4.5) |
| Dialysis | 14 | 10 | 7.7 | 13.6 | 1.7 (0.7 – 3.8) | 2.1 (0.8 – 5.4) |
| Hospitalization | 36 | 25 | 29.2 | 68.1 | 2.0 (1.2 – 3.4) | 1.9 (1.1 – 3.5) |
| Events | Incidence a | |||||
| BAI < 13 | BAI ≥ 13 | BAI < 13 | BAI ≥ 13 | BAI ≥ 13 | BAI ≥ 13 | |
| (n) | (n) | Unadjusted model | Adjusted model b | |||
| Dialysis/Death | 28 | 15 | 15.1 | 21.6 | 1.3 (0.7 – 2.5) | 1.6 (0.8 – 3.2) |
| Composite event c | 48 | 26 | 38.5 | 73.8 | 1.7 (1.0 – 2.8)* | 1.6 (0.9 – 2.7) |
| Death | 11 | 8 | 5.9 | 11.5 | 1.6 (0.6 – 4.0) | 1.5 (0.5 – 4.2) |
| Dialysis | 17 | 7 | 9.2 | 10.1 | 1.1 (0.5 – 2.6) | 1.4 (0.5 – 3.7) |
| Hospitalization | 39 | 22 | 21.0 | 31.7 | 1.7 (0.9 – 2.9) | 1.6 (0.9 – 2.8) |
Values expressed as hazard ratio (95 % confidence interval)
*P < 0.05
aincidence rate of adverse events presented per 1000 person months
bAdjusted for age, gender, history of depression, diabetes, cardiovascular disease and glomerular filtration rate
cComposite event: death, initiation of dialysis or first hospitalization