Table 1. Baseline characteristics of patients with freshly diagnosed pulmonary tuberculosis in the four treatment groups.
| Features | Placebo (n = 72) | PBA (n = 72) | vitD3 (n = 72) | PBA+vitD3 (n = 72) |
|---|---|---|---|---|
| Intention-to-treat group, n = 288 | ||||
| Gender (Males) (Number, %) | 44(61%) | 44(61%) | 44(61%) | 45(62·5%) |
| History of contacts (Number, %) | ||||
| Male | 10(22.7%) | 12(27.3%) | 9(20.5%) | 12(26.7%) |
| Female | 13(46.4%) | 8(28.6%) | 10(35.7%) | 12(44.4%) |
| BCG given (Number, %) | ||||
| Male | 33(75.0%) | 24(54.5%) | 35(79.5%) | 32(77.1%) |
| Female | 13(46.4%) | 20(71.4%) | 20(71.4%) | 21(77.8%) |
| Age, years (Mean±SD) | 26.7±8.1 | 26.8±7.3 | 28.1±9.9 | 26.8±6.9 |
| Weight, kg (Mean±SD) | ||||
| Male | 46.3±6.6 | 48.9±6.5 | 47.9±8.4 | 46.6±6.6 |
| Female | 39.8±7.8 | 37.0±5.7 | 38.4±7.6 | 39.8±7.8 |
| Tuberculin skin test done | 7(2.4%) | 12(4.2%) | 8(2.8%) | 9(3.1%) |
| Duration of illness, days (Mean±SD) | ||||
| Male | 50.9±26.8 | 48.8±20.6 | 55.1±2 6.5 | 53.6±28.7 |
| Female | 51.9±23.5 | 53.6±19.9 | 51.9±26.5 | 47.2±22.9 |
| ESR, mm 1st hr (Mean±SD) | 60.2±34.9 | 56.9±32.5 | 54.0±31.1 | 56.8±33.2 |
| Hb, gm/dl (Mean±SD) | 11.6±1.6 | 11.5±1.7 | 11.3±1.9 | 11.7±1.8 |
| WBC, 1x103/cmm (Mean±SD) | 10.56±2.63 | 9.99±2.16 | 10.93±2.88 | 11.36±3.21 |
| Per-protocol group, n = 249 | ||||
| Vitamin D status # | (n = 64) | (n = 58) | (n = 62) | (n = 65) |
| Vitamin D nmol/L | 28.1±16.2 | 23.8±14.8 | 28.0±17.5 | 26.8±16.3 |
| Deficient, <30 nmol/L | 40(62.5%) | 41(70.7%) | 46(74.2%) | 39(60.0%) |
| Insufficient, 30–50 nmol/L | 19(29.7%) | 13(22.4%) | 8(12.9%) | 20(30.8%) |
| Sufficient, >50 nmol/L | 5(7.8%) | 4(6.9%) | 8(12.9) | 6(9.2%) |
Data is presented as mean ± standard deviation or number with percentage in parentheses. BCG, Bacillus Calmette–Guérin.; ESR, erythrocyte sedimentation rate; Hb, hemoglobin; WBC, white blood cells. History of contacts, BCG given and Tuberculin skin test done are dichotomous variable and age, weight, duration of illness, ESR, Hb, WBC and vitamin D status are continuous variable.