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. Author manuscript; available in PMC: 2015 Sep 22.
Published in final edited form as: Nat Clin Pract Endocrinol Metab. 2007 Jul;3(7):518–529. doi: 10.1038/ncpendmet0554

Table 4.

Randomized, controlled trials for weight-loss maintenance with maintenance intervention then no supervision after exercise intervention for weight loss.

Reference Weight loss intervention duration Weight maintenance intervention duration Unsupervised follow-up duration Total n (completers) Weight regain for diet-only controls Weight regain for diet + exercise Significancea
Borg et al. (2002)44 b 2 months 6 months 23 months 90 M (68) 8 months +1.6 kg 8 months AE +1.8 kg
RE +0.3 kg
NS
NS
31 months +8.4 kg 31 months AE +10.1 kg
RE +9.1 kg
NS
NS

Fogelholm et al. (2000)45 c 12 weeks 40 weeks 2 years 82 F (74) 1 year +2 kg
3 years +9.7 kg
Walk 1f 1 year –0.7 kg
3 years +6.2 kg
NS
P <0.05
Walk 2g 1 year –0.6 kg
3 years +9.5 kg
NS
NS

Leermakers et al. (1999)46 d 6 months 6 months 6 months 67 M and F (48) 18 months +0.8 kg 18 months +4.4 kg P <0.05

Perri et al. (1988)49 e 20 weeks 6 months 12 months 123 M and F (91) BT-only improved weight maintenance compared with controls Exercise did not alter results compared with BT-only; all exercise conditions improved weight maintenance compared with control NS
a

P <0.05 considered significant for difference in weight regain for diet and exercise versus diet control. Intervention involved:

b

VLCD then randomized to control, walking (AE) or resistance training (RE) for maintenance;

c

VLCD then randomized to control vs Walk 1 or Walk 2 interventions for maintenance;

d

Weight loss then randomized to biweekly exercise focused or weight focused maintenance;

e

BT randomized to five arms for maintenance.

f

Walk 1 was 2-3 h per week;

g

Walk 2 was 4-6 h per week.

Abbreviations: AE, aerobic exercise; BT, behavioral therapy; F, female; M, male; NS, not significant; RE, resistance exercise; VLCD, very-low-calorie diet.