. Author manuscript; available in PMC: 2016 Oct 1.

Published in final edited form as: IEEE Trans Biomed Eng. 2015 Apr 29;62(10):2379–2388. doi: 10.1109/TBME.2015.2427745

TABLE III.

The estimated number of pulses and the squares of the multiple correlation coefficients (R²) for the fits to the experimental ACTH and cortisol time series

participant	M	N	$R_{C}^{2}$	$R_{A}^{2}$

1	18	18	0.94	0.74
2	17	17	0.88	0.65
3	16	16	0.94	0.66
4	17	17	0.88	0.73
5	18	15	0.89	0.52
6	20	15	0.92	0.58
7	16	17	0.91	0.51
8	16	16	0.89	0.79
9	16	17	0.83	0.67
10	20	17	0.82	0.46
Median	17	17	0.89	0.66

M is the estimated number of Cortisol pulses using only measurements of Cortisol levels, and N is the estimated number of ACTH pulses using concurrent measurements of ACTH and cortisol levels. $R_{C}^{2}$ and $R_{A}^{2}$ are the square of the multiple correlation coefficient for cortisol and ACTH time series, respectively.