Table 3.
Mean Levels of NM Adduct for CT DNA as a Function of Neutral Thermal Hydrolysis Conditions a
| 95 °C (4 h) | 37 °C (72 h) adducts in supernatant | 95 °C (4 h) after 37 °C (72 h) | Sum of adducts 37 °C (72 h) and 95 °C (4 h) | FPG | |
|---|---|---|---|---|---|
| NM-G | 24.0 ± 1.6 | 33.8 ± 2.0 | 2.2 ± 0.4 | 36.0 ± 1.9 | 33.7 ± 3.0 |
| G-NM-G | 102 ± 3.0 | 75.7 ± 8.7 | 23.0 ± 4.8 | 98.7 ± 7.7 | 99.2 ± 12.3 |
| NM-FapyG | 23.1 ± 1.8 | 0.8 ± 0.1 | 6.1 ± 0.7 | 6.9 ± 0.7 | 8.6 ± 1.0 |
| FapyG-NM-G | 3.6 ± 0.3 | 0.3 ± 0.1 | 3.1 ± 0.6 | 3.4 ± 0.6 | 1.5 ± 0.2 |
a
3 independent measurements (Mean ± SD)