Fig 5. Normalized pathological angiogenesis in Gpr116 -/- retinas.
A. Confocal images of post-OIR retinas from Gpr116 WT, heterozygous and knockout littermates at P12 (the images shown are representative of 5 mice per genotype). B. Confocal images of post-OIR retinas from Gpr116 WT, heterozygous and knockout littermates at P17 (the images shown are representative of 5 mice per genotype). C. Quantification of the avascular area on the post-OIR retinas from Gpr116 WT, heterozygous and knockout littermates at P12 (n = 5 mice at least per genotype). D. Quantification of the avascular area on the post-OIR retinas from Gpr116 WT, heterozygous and knockout littermates at P17 (n≥7 mice at least per genotype). E. Confocal images of post-OIR tufts (blue arrows) in Gpr116 WT, heterozygous and knockout littermates at P17 (the images shown are representative of 5 mice per genotype)