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. 2015 Sep 22;10(9):e0138789. doi: 10.1371/journal.pone.0138789

Fig 3. CBLC and SRC antagonistic effect on the Golgi apparatus.

Fig 3

Giantin staining in HeLa cells. Fragmentation Index measured in quadruplicates on at least 400 cells per condition. Error bars show SD statistical significance (p) measured by unpaired Student’s t-test. (*) represents p<0.05, (**) represents p<0.01 and (***) represents p<0.001. (A and D) Co-transfection of CBLC and SRC siRNAs in HeLa cells (B and E) Treatment of CBLC-depleted cells with SRC inhibitors PP2 or SKI-1 rescues Golgi morphology. (C and F) Co-transfection of CBLC and ARF1 siRNAs in HeLa cells rescues Golgi morphology. Scale bar = 10 μm.