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. 2015 Sep 22;10(9):e0138789. doi: 10.1371/journal.pone.0138789

Fig 4. SRC recruits CBLC to the Golgi apparatus.

Fig 4

(A) CBL and CBLC localize to the Golgi apparatus. MannII-GFP and endogenous CBL, CBLB, or CBLC staining in HeLa cells. (B) SRC activation enhances recruitment of CBLC to the Golgi apparatus. Cells were transfected with either constitutively active SRC E378G or inactive SRC K295M. Staining for tyrosine-phosphorylated proteins stained with pY20 (white) to report SRC transfection and for endogenous CBLC (red). CBLC level at the Golgi was increased in cells overexpressing active SRC (yellow arrow) but not inactive SRC. Scale bar = 10 μm.