Table 1.
Parameter Values for Base Case, One-Way and Probabilistic Sensitivity Analyses
Description | Base | Range | Distribution | Source |
---|---|---|---|---|
Probabilities | ||||
Empiric antibiotics in yr 0 prior to intervention | 75 % | Not varied | Not varied | 10 |
Adjusted odds of antibiotics during intervention | ||||
Relative to baseline, yrs 1–5 | ||||
Usual care (UC) | 1.10 | 0.85–1.43 | Uniform | 10 |
Printed decision support (PDS) | 0.57 | 0.40–0.82 | Uniform | 10 |
Computerized decision support (CDS) | 0.64 | 0.45–0.91 | Uniform | 10 |
Chest x-ray | ||||
UC | 4.2 % | 0 %–10 % | Beta | 10 |
PDS | 3.2 % | 0 %–10 % | Beta | 10 |
CDS | 4.9 % | 0 %–10 % | Beta | 10 |
Return to clinic within 30-days | ||||
UC | 7.6 % | 0 %–15 % | Beta | 10 |
PDS | 7.1 % | 0 %–15 % | Beta | 10 |
CDS | 8.3 % | 0 %–15 % | Beta | 10 |
Emergency department within 30 days | ||||
UC | 0.2 % | 0–3 % | Beta | 10 |
PDS | 1.2 % | 0–3 % | Beta | 10 |
CDS | 0.0 % | 0–3 % | Triangular | 10 |
Hospitalization, within 30 days | ||||
UC | 1.0 % | 0–3 % | Beta | 10 |
PDS | 0.3 % | 0–3 % | Beta | 10 |
CDS | 1.1 % | 0–3 % | Beta | 10 |
Durations | ||||
Hours of education per physician, PDS and CDS, yr 1 | 1.0 | 0.5–1.5 | Triangular | 10 |
Days of work loss due to illness and seeking care, no antibiotics | 3.0 | Not varied | Not varied | 4, Estimate |
Decrease in days of work loss with antibiotics | 0.0 | −1.0–1.0 | Gamma | 4, Estimate |
Costs | ||||
Physician education per hour, PDS and CDS, yr 1 | $120 | $80–$160 | Gamma | 12 |
Educational brochure per patient, PDS and CDS, yrs 1–5 | $0.05 | $0.03–$0.30 | Gamma | 13 |
Exam room poster per patient, PDS, yr 1 | $0.96 | $0.48–$5.76 | Gamma | 13 |
Medical record programming per patient, CDS, yr 1 | $18 | $9–$27 | Gamma | 13 |
Chest x-ray | $31 | $10–$100 | Gamma | 14 |
Antibiotics | $30 | $5–$100 | Gamma | 15, Estimate |
Work loss per day due to illness and seeking care | $136 | $96–$176 | Gamma | 16 |
Clinic visit | $107 | $57–$157 | Gamma | 17 |
Emergency department visit | $680 | $280–$1,080 | Gamma | 18 |
Hospitalization | $5,424 | $4,424–$6,424 | Gamma | 19 |