Fig. 1.

Least squares mean differences from placebo in trough force expiratory volume at 1 s (at various timepoints) with umeclidinium/vilanterol, umeclidinium and vilanterol treatment, by baseline eosinophil subgroup (a–c), and by baseline eosinophil subgroup and concomitant inhaled corticosteroid use (d–f). CI confidence interval, EOS eosinophil, ICS inhaled corticosteroid, LS least squares, UMEC umeclidinium, VI vilanterol