Fig. 5.
NODDI maps of three patients with lesions of different grades, together with ADC and FA maps fitted from the same double-shell data, and 3 T T1-gad and FLAIR images. T2L was outlined, defined as the hyperintensity abnormality in the FLAIR image. Within in the T2L, variations were seen in viso, vic, and vec, reflecting different water mobility characteristics at different parts of the lesion. Contrast enhancing lesions were present in all patients (arrow) and all demonstrated elevated OD and vic. The white arrow indicated two interesting regions at the edge of T2L of the grade II and grade III patients, which could easily be easily missed on anatomical images and DTI maps, but was highlighted due to elevated vec.