Figure 3. SC depletion induces connective tissue accumulation in skeletal muscles after neuromuscular disruption.
(A) Representative images of TA sections stained with H&E; scale bar = 100 μm, (B) Representative images of TA sections stained Sirius Red and pseudocolor images generated by VisioPharm software; numbers indicate myofiber connective tissue (MCT) (red) content in each representative image; scale bar = 50 μm. (C) Quantification of MCT content in TA muscles. N = 4 mice. *p < 0.05 compared to Ctrl-sham, P7DTA-sham and Ctrl-SNT, ANOVA/Bonferroni multiple comparisons test.