Figure 6. Limited SC proliferation in skeletal muscles upon neuromuscular disruption.
(A) Strategy to BrdU label SCs in adult mice 4 weeks after sham or SNT surgery and representative TA sections stained with anti-Pax7 (red), anti-BrdU (green) and anti-Laminin (white). Red arrowheads indicate Pax7+ cell; green arrowhead indicates BrdU + cell; yellow arrowhead indicates BrdU+/Pax7+ cell. (B) Quantification of BrdU+/Pax7+ percentage. N = 3 mice, 3 sections/mouse, 6 fields of view/section. *p < 0.05, t-tests.