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. 2014 Jul 29;1:9. doi: 10.1186/2052-6687-1-9

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© Mitchell et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Example of caudal cranium distribution differences in young affected and older clear individuals. The cranium in the fourth quadrant in the SM clear individual shows an increased coverage of the grid relative to the first, second and third quadrants, resulting in a high percentage distribution in the fourth quadrant of 24%. Conversely, in the early SM affected individual, an increased coverage in the first, second and third quadrants and a decreased coverage in the fourth quadrant leads to a decreased percentage cranium distribution in the fourth quadrant of 12%.