TABLE 7.
Bacterial susceptibility toward thymol in planktonic and biofilm growth modes before, during, and after repeated exposure to thymol in aqueous solution or in formulationa
| Bacterium | Concn (mg/liter) |
|||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MIC |
MBC |
MBEC |
||||||||||||||||
| UF |
F |
UF |
F |
UF |
F |
|||||||||||||
| P0 | P14 | X14 | P0 | P14 | X14 | P0 | P14 | X14 | P0 | P14 | X14 | P0 | P14 | X14 | P0 | P14 | X14 | |
| S. aureus† | 187.5 | 187.5 | NA | 187.5 | 187.5 | NA | 375 | 375 | NA | 375 | 750 | NA | 416 (160) | 375 | NA | 375 | 750 | NA |
| E. coli† | 1,500 | 1,500 | NA | 187.5 | 375 | 375 | 1,500 | 1,500 | NA | 375 | 1,500 | 750 | 1,500 | 1,500 | NA | 375 | 3,000 | 1,500 |
| E. faecalis† | 375 | 750 | NA | 187.5 | 375 | NA | 750 | 750 | NA | 375 | 750 | NA | 750 | 750 | NA | 750 | 1,500 | NA |
| P. aeruginosa† | 3,000 | 3,000 | NA | 1,500 | 3,000 | NA | 6,000 | 3,000 | NA | 3,000 | 6,000 | NA | 6,000 | 6,000 | NA | 6,000 | 12,000 | NA |
| M. osloensis* | 750 | 750 | NA | 187.5 | 375 | NA | 750 | 750 | NA | 187.5 | 375 | NA | 3,000 | 1,500 | NA | 3,000 | 375 | NA |
| A. baumannii* | 750 | 750 | NA | 375 | 375 | 375 | 1,500 | 3,000 | NA | 750 | 6,000 | 3,000 | 6,000 | 6,000 | NA | 6,000 | 6,000 | 6,000 |
| P. putida* | 750 | 750 | NA | 375 | 3,000 | 375 | 1,500 | 3,000 | NA | 1,500 | 6,000 | 3,000 | 6,000 | 6,000 | NA | 6,000 | 6,000 | 12,000 |
| C. sakazakii* | 750 | 750 | NA | 375 | 375 | NA | 2,250 (822) | 3,000 | NA | 375 | 750 | NA | 6,000 | 6,000 | NA | 3,000 | 750 | NA |
| E. coli* | 665 (190) | 750 | NA | 187.5 | 375 | NA | 3,000 | 3,000 | NA | 375 | 750 | NA | 6,000 | 6,000 | NA | 750 | 3,000 | 1,500 |
a
See footnote in Table 1.