FIG 3.
Superantigenic activity of SElY in mouse splenocytes. Mouse splenocytes were incubated with various concentrations of SEA, SET, and SElY for 72 h. (A) The uptake of [3H]thymidine was determined to assess lymphocyte proliferation. (B and C) The production of IFN-γ (Β) and IL-2 (C) was determined by sandwich ELISAs. Mock, mock treatment with no toxin. Each bar represents the mean ± standard deviation for triplicate wells from a representative experiment. These data were reproducible in three experiments.