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. 2015 Jun 30;9(10):2162–2177. doi: 10.1038/ismej.2015.28

Table 2. Network analysis on stepwise-added metagenomes.

# Metagenomes 1a 2b 3c 4d 5e 6f 7g 8h 9i
Contigs 211 2202 6148 9963 14 741 19 977 24 527 28 134 30 132
Edges 942 10 012 36 665 68 197 121 704 186 584 237 728 277 340 304 585
Average degree 8.929 9.094 11.927 13.690 16.512 18.680 19.385 19.716 20.217
Modularity 0.682 0.923 0.946 0.957 0.956 0.956 0.956 0.959 0.959
Viral groups 8 28 55 68 81 84 92 103 105
Avg. clustering coefficient 0.688 0.720 0.750 0.765 0.770 0.768 0.766 0.766 0.766
# Metagenomes 1j 2k 3l 4m 5n 6o 7p 8q 9r
Contigs   509 3583 9120 13 995 17 776 22 889 26 618 30 132
Edges   1344 12 711 39 773 78 338 115 037 178 631 238 101 304 585
Average degree   5.281 7.095 8.722 11.195 12.943 15608 17.89 20.217
Modularity   0.900 0.962 0.969 0.962 0.965 0.962 0.961 0.958
Viral groups   19 51 86 94 106 108 105 105
Avg. clustering coefficient   0.650 0.712 0.730 0.742 0.751 0.758 0.764 0.766
a

0809.

b

0809-0901.

c

0809-0903.

d

0809-0904.

e

0809-0908.

f

0809-0909.

g

0809-0910.

h

0809-1002.

i

0809-1006.

j

Did not have a major population.

k

1006-1002.

l

1006-0910.

m

1006-0909.

n

1006-0908.

o

1006-0904.

p

1006-0903.

q

1006-0901.

r

1006-0809.

The 9 454 metagenomes were added one-by-one successively to the previous metagenome (1, 1+2, 1+2+3, etc.) and analyzed using the network-based analysis. The number of contigs present in the network is given under ‘Contigs' with the number of connections between all contigs as ‘Edges.' Average degree refers to the average number of connections incoming/outgoing from each contig and denotes relative connectivity between contigs. Modularity is a measure of separation and distinction of viral groups. The greater the value (approaches 1) the more connections tend to exist between members within a viral group than between members of differing viral groups. This also serves as a measure of the overall organizational level of the network, with values >0.3 indicating community structure. The average clustering coefficient measures how well contigs tend to associate with each other.