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Methylation frequency (%) comparison of SFRP CpG sites in three tissue groups
| Genes | No. of CpG islands | Frequency of promoter methylation (%) | ||
|---|---|---|---|---|
| T vs. N | T vs. A | A vs. N | ||
| SFRP1 | 17 | 82.35 (14/17) | 58.82 (10/17) | 29.41 (5/17) |
| SFRP2 | 14 | 50 (7/14) | 57.14 (8/14) | 42.86 (6/14) |
| SFRP4 | 18 | 72.22 (13/18) | 72.22 (13/18) | 61.11 (11/18) |
| SFRP5 | 11 | 54.54 (6/11) | 54.54 (6/11) | 54.54 (6/11) |
| P*-value | <0.05 | <0.05 | <0.05 | |
T tumor tissues; A adjacent tissues; N normal samples
*Nonparametric Mann-Whitney U test
