Table III.
Associations of VEGF-C/VEGFR-3 expression with clinicopathological factors.
| VEGF-C/VEGFR-3 | |||
|---|---|---|---|
| Characteristics | – | + | P-value |
| Age (years) | 0.605 | ||
| >65 | 9 | 20 | |
| ≤65 | 14 | 22 | |
| Gender | 0.799 | ||
| Male | 13 | 22 | |
| Female | 10 | 20 | |
| T stage | 0.408 | ||
| T1 + T2 | 17 | 21 | |
| T3 + T4 | 6 | 21 | |
| Differentiation | 0.546 | ||
| High | 23 | 39 | |
| Moderate/poor | 0 | 3 | |
| Pattern of invasion | 0.142 | ||
| Grades 1/2 | 22 | 34 | |
| Grades 3/4 | 1 | 8 | |
| Clinical growth pattern | 0.0001 | ||
| Superficial + exophytic | 21 | 18 | |
| Endophytic | 2 | 24 | |
| Regional recurrence | 0.0235 | ||
| No | 22 | 30 | |
| Yes | 1 | 12 | |
| Depth of invasion (mm) | 0.0009 | ||
| <4 | 21 | 21 | |
| ≥4 | 2 | 21 | |
VEGF-C, vascular endothelial growth factor-C; VEGFR-3, vascular endothelial growth factor receptor-3.