Table IV.
Clinicopathological characteristics and VEGF-C/VEGFR-3 expression in association with regional recurrence.
| Regional recurrence | |||||
|---|---|---|---|---|---|
| Characteristics | – | + | Odds ratio | 95% CI | P-value |
| Age (years) | 0.628 | 0.185–2.13 | 0.456 | ||
| >65 | 22 | 7 | |||
| ≤65 | 30 | 6 | |||
| Gender | 2.250 | 0.615–8.23 | 0.221 | ||
| Male | 26 | 9 | |||
| Female | 26 | 4 | |||
| T stage | 4.250 | 1.148–15.73 | 0.031 | ||
| T1 | 34 | 4 | |||
| T2 | 18 | 9 | |||
| Differentiation | 9.270 | 0.770–111.54 | 0.079 | ||
| High | 51 | 11 | |||
| Moderate/poor | 1 | 2 | |||
| Pattern of invasion | 81.600 | 8.400–791.90 | <0.001 | ||
| Grades 1/2 | 47 | 5 | |||
| Grades 3/4 | 5 | 8 | |||
| Clinical growth pattern | 32.570 | 3.800–274.10 | <0.010 | ||
| Superficial + exophytic | 38 | 1 | |||
| Endophytic | 14 | 12 | |||
| Depth of invasion (mm) | 44.700 | 5.200–382.40 | <0.001 | ||
| <4 | 41 | 1 | |||
| ≥4 | 11 | 12 | |||
| VEGF-C/VEGFR-3 | 8.800 | 1.060–72.79 | 0.024 | ||
| Negative | 22 | 1 | |||
| Positive | 30 | 12 | |||
VEGF-C, vascular endothelial growth factor-C; VEGFR-3, vascular endothelial growth factor receptor-3; CI, confidence interval.