Table VI.
Associations between lymphatic vessel counts and the progression of lymph node metastasis and protein expression of VEGF-C/VEGFR-3.
| Parameters | Mean lymphatic vessel countsa | P-value |
|---|---|---|
| VEGF-C | <0.0001 | |
| Negative | 8.571±8.182 | |
| Positive | 17.176±8.757 | |
| VEGFR-3 | <0.0001 | |
| Negative | 10.379±7.439 | |
| Positive | 19.306±8.784 | |
| VEGF-C/VEGFR-3 | <0.0001 | |
| Negative | 9.217±7.552 | |
| Positive | 18.666±9.333 | |
| pN classification | <0.0001 | |
| pN0 | 13.166±8.659 | |
| pN1/2 | 25.727±5.515 | |
| pN classification | 0.099 | |
| pN1 | 29.500±6.908 | |
| pN2 | 23.600±2.702 | |
| Extracapsular spread | 0.146 | |
| Negative | 30±7.127 | |
| Positive | 22.5±4.670 |
a
Data are presented as means ± standard deviation. VEGF-C, vascular endothelial growth factor-C; VEGFR, vascular endothelial growth factor receptor-3.