Table II.
Tumor type | AnxA6 expression pattern | Implication | Ref. |
---|---|---|---|
CC | High expression levels in SCC | AnxA6 is a potential marker of CC diagnostics and prognosis | (27,31,40) |
ALL | High expression levels in samples of patients with ALL and in B-lineage ALL cells | AnxA6 is a candidate marker for monitoring minimal residual disease in B-lineage ALL | (33) |
Large-cell lymphoma | High expression levels in mouse high metastatic RAW117 cells | Localized expression of AnxA6 is associated with the metastasis and adhesion of lymphoma cells | (45) |
Myeloma | Upregulation of AnxA6 is associated with overexpression of TPD52 | AnxA6 promotes tumorigenesis of B-cell malignancies associated with TPD52 | (21) |
AnxA6, annexin A6; CC, cervical cancer; SCC, squamous cell cervical carcinoma; ALL, lymphoblastic leukemia; TPD52, tumor protein D52.