Table VI.
Distribution of KRAS mutations according to smoking history.
| Type of KRAS mutation | Smokers (%) | Ex-smokers (%) | Non-smokers (%) |
|---|---|---|---|
| Transversion mutation | |||
| c.35G>T (p.G12V) | 26/65 (40) | 6/13 (46.15) | 10/28 (35.71) |
| c.34G>T (p.G12C) | 18/65 (27.69) | 5/13 (38.46) | 5/28 (17.86) |
| c.37G>T (p.G13C) | 9/65 (13.85) | 2/13 (15.38) | 1/28 (3.57) |
| Total | 53/65 (81.54) | 13/13 (100) | 16/28 (57.14) |
| Transition mutation | |||
| c.35G>A (p.G12D) | 10/65 (15.38) | 0/13/(0) | 9/28 (32.14) |
| c.38G>A (p.G13D) | 2/65 (3.08) | 0/13/(0) | 2/28 (7.14) |
| c.34G>A (p.G12S) | 0/65 (0) | 0/13/(0) | 1/28 (3.57) |
| Total | 12/65 (18.46) | 0/13 (0) | 12/28 (42.86) |
KRAS, Kirsten-rat sarcoma oncogene homolog.