Table III.
Evaluation of available patient data for ALDH1A1 expression and HPV status.a
| Evaluation of patient data, n (%) | ||||
|---|---|---|---|---|
| Factor | ALDH1A1+ | ALDH1A1+/HPV− | ALDH1A1− | ALDH1A1−/HPV− |
| Total patients | 26 (100.0) | 19 (100.0) | 22 (100.0) | 21 (100.0) |
| Gender | ||||
| Male | 20 (76.9) | 14 (73.7) | 15 (68.2) | 15 (71.4) |
| Female | 6 (23.1) | 5 (26.3) | 7 (31.8) | 7 (33.3) |
| Cancer relapse | ||||
| Positive | 6 (23.1) | 6 (31.6) | 12 (54.5) | 12 (57.1) |
| Negative | 20 (76.9) | 13 (68.4) | 10 (45.5) | 9 (42.9) |
| Age, years | ||||
| <60 | 10 (38.5) | 7 (36.8) | 13 (59.1) | 12 (57.1) |
| 60–70 | 9 (34.6) | 9 (47.4) | 7 (31.8) | 7 (33.3) |
| >70 | 7 (26.9) | 3 (15.8) | 2 (9.1) | 2 (9.5) |
| T stage | 25 (100.0) | 18 (100.0) | 18 (100.0) | 17 (100.0) |
| T1 | 0 (0.0) | 0 (0.0) | 4 (22.2) | 4 (23.5) |
| T2 | 12 (48.0) | 9 (50.0) | 7 (38.9) | 7 (41.2) |
| T3 | 9 (36.0) | 5 (27.8) | 5 (27.8) | 4 (23.5) |
| T4 | 4 (16.0) | 4 (22.2) | 2 (11.1) | 2 (11.8) |
| N stage | 24 (100.0) | 17 (100.0) | 18 (100.0) | 17 (100.0) |
| N0 | 8 (33.3) | 4 (23.5) | 6 (33.3) | 6 (35.3) |
| N1-N3 | 16 (66.7) | 13 (76.5) | 12 (66.7) | 11 (64.7) |
Patients with ALDH1A1+ tumors exhibited a reduced risk for relapse (P≤0.05). Metastasis into lymph nodes (N status) between ALDH1A1+ and ALDH1A1− tumors was equal. ALDH1A1, aldehyde dehydrogenase 1 family, member A1; CD44, hyaluronan receptor cluster of differentiation 44; HPV, human papilloma virus.