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. 2015 Sep 22;15:643. doi: 10.1186/s12885-015-1648-4

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© Paiva et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The overall survival curves from the start of bevacizumab treatment. Overall survival curve from the total cohort (n = 105 patients), median of 24.4 months (a). Overall survival curves according to: ECOG (1 = ECOG 0, 1 vs. 2 = ECOG 2, 3), p = 0.001 (b); histogical grade (well differentiated = grade 1, moderately differentiated = grade 2 vs. poorly differentiated = grade 3), p = 0.006 (c); liver metastasis (yes vs. no), p < 0.001 (d); lymph node metastasis (yes vs. no), p = 0.004 (e), and patients who underwent metastasis resection (yes vs. no), p < 0.001 (f). The survival curves were calculated using the Kaplan-Meier method, and the log-rank test was used for comparison. ECOG: Eastern Cooperative Oncology Group performance status score