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. 2015 Sep 22;15:643. doi: 10.1186/s12885-015-1648-4

Table 2.

Association between clinical variables and objective response by RECIST

Variable Total n CR + PR n (%) SD + PD n (%) p value
Grade 1 + 2 74 42 (57) 32 (43) 0.01
3 9 1 (11) 8 (89)
Mucinous histology no 84 46 (55) 38 (45) 0.048
yes 10 2 (20) 8 (80)
Liver metastasis no 31 8 (26) 23 (74) 0.001
yes 64 40 (62) 24 (38)
Peritoneal metastasis no 79 43 (54) 36 (46) 0.09
yes 16 5 (31) 11 (69)
Chemotherapy FOLFIRI 52 25 (48) 27 (52) 0.43
FOLFOX 39 22 (56) 17 (44)
Hypertension no 61 29 (47) 32 (53) 0.41
yes 30 17 (57) 13 (43)
Chemo + bevacizumab as first-line therapya no 28 9 (36) 19 (64) 0.02
yes 67 40 (60) 27 (40)

RECIST: Response Evaluation Criteria in Solid Tumors; FOLFIRI: infusional 5-fluoro-uracyl plus leucovorin plus irinotecan; FOLFOX: infusional 5-fluoro-uracyl plus leucovorin plus oxaliplatin; CR: Complete Response; PR: Partial Response; SD: Stable Disease; PD: Progressive Disease (PD). Data are number of patients and numbers in parentheses are percentages. aChemo: chemotherapy