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. 2015 Sep 23;13:313. doi: 10.1186/s12967-015-0659-x

Fig. 12.

Fig. 12

Reporter gene imaging. Reporter gene inserted in the downstream of a gene promoter. The promotor activation transcribes reporter gene to reporter mRNA, which produces reporter protein after translation. The reporter protein converts the substrate or probe into active form which can be imaged using MRI