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. 2015 Sep 23;13:313. doi: 10.1186/s12967-015-0659-x

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© Haris et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — pH mapping of tumor tissue. Anatomical image is showing a subcutaneously implanted EL4 tumor. The pH map generated by calculating the ratio of the hyperpolarized H¹³CO3 and ¹³CO2 voxel intensities using handersal-hasselbatch equation. Reproduced with permission from the Nature Publishing Group and Gallagher et al. [78]