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. 2015 Jul 30;10(4):2075–2080. doi: 10.3892/ol.2015.3548

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Copyright: © Wu et al. This is an open access article distributed under the terms of a Creative Commons Attribution License.

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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Figure 3. — IF1 knockdown suppresses the migration and invasion of glioma cells. (A) U251 and U87 cells transfected with NT shRNA or IF1 shRNA were analyzed using western blotting to detect IF1 expression. Experiments were repeated in triplicate, with similar results. (B) Cell migration was measured by Transwell assays and was inhibited by IF1 knockdown in U251 and U87 cells, as compared with control cells (n=6). *P<0.05 vs. control. (C) Downregulation of IF1 in U215 and U87 cells conferred a decreased number of invaded cells compared with control cells (n=6). *P<0.05 vs. control. IF1, adenosine triphosphatase inhibitory factor 1; NT, non-targeting; shRNA, short hairpin RNA; HPF, high power fields.