Table 3.
Adverse events during treatment
| Hybrid therapy | Sequential therapy | P value | |
| Compliance, n (%) | 84 (97.7) | 83 (97.6) | 0.99 |
| Side effects, n (%) | 52 (59) | 60 (69) | 0.22 |
| Diarrhea | 16/1/11 | 15/0/0 | 0.42 |
| Constipation | 1/0/0 | 2/0/0 | 0.50 |
| Anorexia | 0 | 1/0/0 | 0.70 |
| Nausea | 4/1/0 | 9/0/1 | 0.92 |
| Vomiting | 5/2/0 | 3/1/0 | 0.57 |
| Abdominal pain | 5/0/0 | 9/0/0 | 0.87 |
| Skin rash | 3/2/0 | 1/2/0 | 0.74 |
| Headache | 9/1/1 | 16/1/1 | 0.41 |
| Dizziness | 6/1/0 | 9/0/0 | 0.70 |
| Bitter taste | 25/6/0 | 36/3/0 | 0.17 |
| Fatigue | 3/0/0 | 4/0/0 | 0.30 |
1
Numbers of patients who suffered from, mild, moderate, and severe adverse events.