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. 2015 Aug 19;10(4):2197–2203. doi: 10.3892/ol.2015.3624

Table I.

The associations between P53 and Cox-2 expression and P53/Cox-2 co-expression and the assessed clinical factors.

P53 expression Cox-2 expression P53 and Cox-2 co-expression



Clinical factors Total High n=118 Low n=77 P-value High n=136 Low n=59 P-value P53(+) Cox-2(+) n=84 Other groups n=111 P-value
Age (years) 0.028a 0.641 0.056
  <60     68   34 34     46 22   23 45
  ≥60   127   84 43     90 37   61 66
Gender 0.538 0.378 0.635
  Female     45   29 16     29 16   18 27
  Male   150   89 61   107 43   66 84
Differentiation 0.015a 0.200 0.020a
  High     16   13   3     10   6     8   8
  Moderate   108   56 52     71 37   37 71
  Poor     71   49 22     55 16   39 32
Position 0.078 0.285 0.560
  Upper       7     7   0     3   4     3   4
  Middle   155   90 65 110 45   64 91
  Lower     33   21 12   23 10   17 16
TNM stage 0.499 0.309 0.662
  I     22   12 10   14   8     8 14
  II     91   59 32   60 31   38 53
  III     82   47 35   62 20   38 44
a

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