Table 5.
Cox Proportional‐Hazard Model for Major Clinical Outcomes
| Baseline Variables Included in the Model (P<0.10) | GD vs NGD Group | |||
|---|---|---|---|---|
| Adjusted Hazard Ratio | Un‐Adjusted P Value | Adjusted P Value | ||
| Death | Age, sex, Charlson index, CHF, CAD, HTN, HL | 0.97 | 0.376 | 0.698 |
| First AF recurrence | Age, Charlson index, CAD | 0.86 | 0.005 | <0.001 |
| Stroke | Age, sex, CHA2DS2‐VASc score, CHF, HTN, COPD | 1.08 | 0.759 | 0.581 |
| First cardiac admission | Age, sex, CHF, CAD | 0.93 | 0.351 | 0.090 |
| First AF admission | Age, sex, CHA2DS2‐VASc score, HTN, HL, CKD | 0.87 | 0.083 | 0.007 |
| First CHF admission | Age, CHA2DS2‐VASc score, CAD, CHF, HTN, COPD, CKD | 1.04 | 0.428 | 0.719 |
| Electrical cardioversion | Age, sex, CHA2DS2‐VASc score, Charlson index, CHF, CAD, valvular disease, COPD | 0.81 | 0.046 | 0.002 |
| AF ablation | Age, CHA2DS2‐VASc score, Charlson index, CAD, HTN, valvular disease, HL, CKD | 0.84 | 0.599 | 0.033 |
| Pacemaker implantation | Age, sex, valvular disease, HL | 0.77 | 0.001 | 0.004 |
| AV nodal ablation | Sex, CHF, CKD | 0.73 | 0.013 | 0.005 |
| Maze surgery | Age, CHA2DS2‐VASc score, valvular disease, HL, COPD | 0.78 | 0.162 | 0.176 |
AF indicates atrial fibrillation; AV, atrioventricular; CAD, coronary artery disease; CHF, congestive heart failure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; GD, guideline‐directed group; HL, hyperlipidemia; HTN, hypertension; NGD, non–guideline‐directed group.