Table 2.
ω6 and ω3 Fatty Acid Composition in Tails of Mice
WT (n=6) | fat‐1 (n=5) | Ffar4−/− (n=6) | Ffar4−/−/fat‐1 (n=6) | |
---|---|---|---|---|
C18:2 (ω6; LA) | 19.7±2.7 | 18.3±2.1 | 19.0±1.8 | 13.9±1.7 |
C18:3 (ω6; GLA) | 0.1±0 | 0.1±0 | 0.2±0.1 | 0.1±0 |
C20:4 (ω6; AA) | 4.5±0.8 | 0.5±0.1* | 4.8±0.7 | 0.7±0.1** |
C18:3 (ω3; ALA) | 0.1±0 | 1.6±0.1* | 0.1±0 | 1.9±0.1** |
C20:5 (ω3; EPA) | ND | 1.1±0.2 | ND | 1.3±0.1 |
C22:5 (ω3; DPA) | 0.2±0 | 0.8±0.1* | 0.1±0.1 | 0.9±0.1** |
C22:6 (ω3; DHA) | 0.8±0.1 | 1.4±0.1* | 0.9±0.2 | 1.3±0.1* |
ω6 PUFAs | 26.0±1.9 | 19.6±2.0* | 25.9±1.3 | 16.0±1.7** |
ω3 PUFAs | 1.0±0.1 | 4.9±0.3* | 1.1±0.3 | 5.5±0.2** |
ω6/ω3* | 27.4±4.3 | 4.1±0.7* | 28.8±4.5 | 2.9±0.3** |
Tails of mice were collected for analysis of fatty acids by gas chromatography flame ionization detection. Values, which are expressed as an area percentage of total measured fatty acids, are shown as mean±SEM. AA indicates arachidonic acid; ALA, α‐linolenic acid; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; GLA, γ‐linolenic acid; LA, linoleic acid; ND, not detectable; PUFAs, polyunsaturated fatty acids; WT, wild type.
P<0.01 compared with WT.
P<0.05 compared with WT.
P<0.01 compared with Ffar4−/−, determined by 1‐way ANOVA post hoc analysis.
The mean of the ratios of 2 variables is not exactly equal to the ratio of their means.