Table 9.

Hazard Ratios (HR) for Heart Rate, per 10 bpm Increase (Atrial Fibrillation Patients, n=20 197)

Outcome	Unadjusted Model			Adjusted Model
	HR	95% CI	P Value	HR	95% CI	P Value
Mortality
LVEF ≤40%
Heart rate <75 bpm	1.050	0.988, 1.117	0.1178	1.048	0.980, 1.120	0.1703
Heart rate ≥75 bpm
[0, 30] days	1.311	1.240, 1.387	<0.0001	1.220	1.130, 1.316	<0.0001
[31, 365] days	0.991	0.943, 1.041	0.7090	1.005	0.953, 1.059	0.8634
LVEF >40%
Heart rate <75 bpm	1.101	1.046, 1.159	0.0002	1.117	1.057, 1.180	<0.0001
Heart rate ≥75 bpm
[0, 30] days	1.315	1.252, 1.380	<0.0001	1.234	1.156, 1.316	<0.0001
[31, 365] days	1.082	1.040, 1.125	<0.0001	1.080	1.035, 1.126	0.0004
All‐cause readmission
LVEF ≤40%
Heart rate <75 bpm	1.010	0.964, 1.058	0.6845	1.008	0.960, 1.057	0.7588
Heart rate ≥75 bpm
[0, 30] days	1.115	1.067, 1.165	<0.0001	1.127	1.076, 1.180	<0.0001
[31, 365] days	0.933	0.892, 0.976	0.0023	0.931	0.889, 0.975	0.0024
LVEF >40%
Heart rate <75 bpm	1.011	0.975, 1.049	0.5601	1.017	0.980, 1.056	0.3806
Heart rate ≥75 bpm
[0, 30] days	1.081	1.039, 1.123	<0.0001	1.094	1.051, 1.139	<0.0001
[31, 365] days	1.009	0.975, 1.044	0.6187	1.018	0.982, 1.055	0.3289
Composite readmission/mortality
LVEF ≤40%
Heart rate <75 bpm	1.009	0.967, 1.053	0.6788	1.006	0.962, 1.053	0.7826
Heart rate ≥75 bpm
[0, 30] days	1.172	1.129, 1.217	<0.0001	1.141	1.093, 1.191	<0.0001
[31, 365] days	0.946	0.908, 0.985	0.0075	0.950	0.910, 0.991	0.0183
LVEF >40%
Heart rate <75 bpm	1.012	0.978, 1.047	0.4974	1.021	0.985, 1.058	0.2575
Heart rate ≥75 bpm
[0, 30] days	1.145	1.108, 1.183	<0.0001	1.108	1.067, 1.150	<0.0001
[31, 365] days	1.030	0.997, 1.063	0.0729	1.031	0.997, 1.066	0.0707

bmp indicates beats per minute; LVEF, left ventricular ejection fraction.