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. 2015 Aug 12;10(4):2003–2008. doi: 10.3892/ol.2015.3601

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Copyright: © Liu et al. This is an open access article distributed under the terms of a Creative Commons Attribution License.

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 4.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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Figure 5. — Tumor volumes of patient-derived CNCAS028 gastric cancer xenografts in response to PHA665752 or/and NVP-BGJ398 treatment, indicating the anti-tumor effect of each treatment. Nude mice bearing PHA665752-resistant CNCAS028 tumors were treated with 30 mg/kg PHA665752 once-daily by i.v. injection, 15 mg/kg NVP-BGJ398 orally or combination therapy for 3 weeks. **P<0.01 vs. vehicle. i.v., intravenous; SD, standard deviation.