Table IV.
Analysis of histological features in predicting the outcome of patients with NB.
| Feature | Total, n | 3-year OS | P-value | 3-year EFS | P-value |
|---|---|---|---|---|---|
| Pathology | |||||
| FH | 13 | 1.00±0.00 | 0.046 | 1.00±0.00 | 0.03 |
| UH | 32 | 0.63±0.12 | 0.36±0.17 | ||
| INPC | |||||
| NB | 36 | 0.83±0.07 | 0.808 | 0.45±0.19 | 0.382 |
| GNB | 9 | 0.50±0.35 | 0.50±0.35 | ||
| Stroma | |||||
| R/M | 3 | 1.00±0.00 | 0.568 | 1.00±0.00 | 0.479 |
| Poor | 42 | 0.78±0.09 | 0.66±0.10 | ||
| MKI | |||||
| H/I | 34 | 0.64±0.13 | 0.718 | 0.49±0.13 | 0.794 |
| Low | 11 | 0.59±0.19 | 0.59±0.19 | ||
| Differentiation | |||||
| UD/PD | 25 | 0.86±0.08 | 0.458 | 0.44±0.19 | 0.943 |
| D | 11 | 0.81±0.12 | 0.81±0.12 |
Data are expressed as the mean ± standard error. FH, favorable histology; UH, unfavorable histology; INPC, International Neuroblastoma Pathology Classification; NB, neuroblastoma; GNB, ganglioneuroblastom; R/M, rich/mix; H/I, high/intermediate; UD/PD, undifferentiated/poorly differentiated; D, differentiated; OS, overall survival; EFS, event-free survival; SE, standard error.