Table 1.

Preparation of fortified antibiotic eye drops

Antibiotic	Method	Final concentration
Cefazolin/cefuroxime	Add 10 ml sterile water to 500 mg cefazolin powder; mix and use as topical drops. Shelf life: 5 days	50 mg/ml (5%)
Gentamicin (tobramycin)	Add 2 ml parenteral gentamicin (40 mg/ml) to a 5 ml bottle of commercial ophthalmic gentamicin (3 mg/ml)	14 mg/ml (1.4%)
Penicillin G	Add 10 ml of artificial tears to a 1 million unit vial of Penicillin G powder; mix and decant into empty artificial tear bottle or xylocaine vials (30 ml)	100,000 units/ml
Vancomycin	Add 10 ml sterile water to a 500 mg vial of vancomycin powder; mix, add sterile cap and use immediately	50 mg/ml (5%)
Amikacin	Add 2 ml of parenteral amikacin containing 200 mg of the antibiotic to 8 ml artificial tears or sterile water in a sterile empty vial.	20 mg/ml (2%)