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. 2015 Jul 24;10(4):2584–2590. doi: 10.3892/ol.2015.3531

Table II.

Univariate and multivariate analyses of prognostic factors for non-small cell lung cancer patients subsequent to treatment with platinum-based chemotherapy.

Univariate analysis Multivariate analysis


Variable HR (95% CI) P-value HR (95% CI) P-value
CTR1 expression
  High vs. low 0.15 (0.62–0.38) 0.000 0.29 (0.11–0.75) 0.010
ATP7A expression
  High vs. low   7.20 (2.48–20.87) 0.000   3.68 (1.11–12.12) 0.032
ATP7B expression
  High vs. low 1.78 (0.78–4.03) 0.168 0.77 (0.29–2.00) 0.592
Gender
  Male vs. female 0.29 (0.10–0.85) 0.023 0.28 (0.09–0.95) 0.040
Age
  ≥60 vs. <60 years 0.97 (0.93–1.00) 0.083 0.96 (0.92–1.01) 0.120
Tumor differentiation
  Good/moderate vs. poor 0.31 (0.19–0.49) 0.000 0.44 (0.24–0.79) 0.006

HR, hazard ratio; CI, confidence interval; CTR1, copper transporter 1; ATP7A, copper-transporting p-type adenosine triphosphatase 1; ATP7B, copper-transporting p-type adenosine triphosphatase 2.