Table 2.
Comparison of liver function tests at week 4 after initiation of antituberculosis drugs
| Silymarin | Placebo | p-value | |
|---|---|---|---|
| (N = 27) | (N = 28) | ||
| ALT (IU/L) | 32 (20, 184) | 35 (15, 415) | 0.455 |
| AST (IU/L) | 26 (14, 219) | 29 (13, 386) | 0.888 |
| ALP (IU/L) | 78 (37, 409) | 85 (56, 249) | 0.622 |
| GGT (IU/L) | 61 (13, 224) | 99 (21, 366) | 0.215 |
| TP (g/L) | 74.2 (25.1, 90.8) | 73.3 (48.7, 93.7) | 0.920 |
| Alb (g/L) | 33.6 (8, 41) | 35.0 (19, 69) | 0.565 |
| TB (mg/dl) | 0.6 (0.2, 2.2) | 0.6 (0.2, 6.5) | 0.999 |
| DB (mg/dl) | 0.3 (0.1, 1.4) | 0.3 (0.1, 5.0) | 0.999 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; GGT, gamma-glutamyl transpeptidase; TP, total protein; Alb, albumin; TB, total bilirubin; DB, direct bilirubin
Continuous variables reported as median (interquartile range)