TABLE 2.

Gene Ontology annotation of proteins identified in FFZE fractions 48 and 49 of Yuc8-infected cells^a

Process or function	Cells for which GO annotation was determined
Biological processes
Generation of energy	Mock-infected cells
Glutamine metabolic process	Mock-infected cells
Hexose metabolic process	Mock-infected cells
Regulation of translation	Mock-infected cells
Respiratory electron transport chain	Mock-infected cells
Cell junction organization	Yuc8-infected cells
Cholesterol biosynthetic process	Yuc8-infected cells
De novo posttranslational folding	Yuc8-infected cells
Mitochondrial ATP synthesis-coupled proton transport	Yuc8-infected cells
mRNA metabolic process	Yuc8-infected cells
Protein localization in mitochondria	Yuc8-infected cells
SRP-dependent cotranslational protein targeting the membrane	Yuc8-infected cells
RNA processing	Yuc8-infected cells
Vesicle targeting to and from within Golgi apparatus	Yuc8-infected cells
Actin filament organization	Both mock-infected and Yuc8-infected cells
ATP biosynthetic process	Both mock-infected and Yuc8-infected cells
Glucose catabolic process	Both mock-infected and Yuc8-infected cells
Protein N-linked glycosylation	Both mock-infected and Yuc8-infected cells
Regulation of translation initiation	Both mock-infected and Yuc8-infected cells
Molecular functions
Cytochrome c oxidase activity	Mock-infected cells
Nucleic acid binding	Mock-infected cells
Protein phosphatase binding	Mock-infected cells
rRNA binding	Mock-infected cells
Actin filament binding	Both mock-infected and Yuc8-infected cells
mRNA binding	Both mock-infected and Yuc8-infected cells
RNA binding	Both mock-infected and Yuc8-infected cells
Translation factor activity	Both mock-infected and Yuc8-infected cells
Unfolded protein binding	Both mock-infected and Yuc8-infected cells
Acetyl coenzyme A acetyltransferase activity	Yuc8-infected cells
ATPase activity to transmembrane movement of ions	Yuc8-infected cells
Hydrogen transporter activity	Yuc8-infected cells

^aGO annotations were determined using the ClueGO plug-in in the protein-protein interaction network visualized by Cytoscape. SRP, signal recognition particle.